mast cell

noun

: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (such as histamine and heparin) which mediate allergic reactions

Examples of mast cell in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
There are topical treatments that are antihistamines, mast cell stabilizers or a combination of both. Neelam Patadia, The Conversation, 27 May 2026 Later, those mast cells split again, giving rise to red blood cells and prototypic T cells. Mrigakshi Dixit, Interesting Engineering, 25 May 2026 This happens because mast cells build up in your bone marrow and release chemical messengers that increase bone breakdown. Brittany Dube, Health, 21 May 2026 Histamine is a chemical compound naturally produced by immune cells, including mast cells, in response to a threat like an allergen. Kara Smythe, EverydayHealth.com, 15 May 2026 See All Example Sentences for mast cell

Word History

Etymology

partial translation of German Mastzelle, from Mast food, mast (from Old High German) + Zelle cell

First Known Use

circa 1890, in the meaning defined above

Time Traveler
The first known use of mast cell was circa 1890

Browse Nearby Words

Cite this Entry

“Mast cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mast%20cell. Accessed 31 May. 2026.

Medical Definition

mast cell

noun
: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions

More from Merriam-Webster on mast cell

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster