mast cell

noun

: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (such as histamine and heparin) which mediate allergic reactions

Examples of mast cell in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This injectable medication targets your immune system and prevents mast cell activation. Zia Sherrell, Health, 17 Feb. 2026 Eye irritation: The same mast cells reside inside your eyes, as well, and can trigger eye itching, swelling, redness, and tearing. Rae Ford, Martha Stewart, 24 Jan. 2026 Stress also makes mast cells, which are the cells involved in allergies and hives, more sensitive, Dr. Wada explains. Korin Miller, SELF, 1 Dec. 2025 Next, Platts-Mills sent some of the blood to the Mayo Clinic lab, which tested it for an enzyme called tryptase that’s made by immune cells called mast cells. Brenda Goodman, CNN Money, 14 Nov. 2025 See All Example Sentences for mast cell

Word History

Etymology

partial translation of German Mastzelle, from Mast food, mast (from Old High German) + Zelle cell

First Known Use

circa 1890, in the meaning defined above

Time Traveler
The first known use of mast cell was circa 1890

Browse Nearby Words

Cite this Entry

“Mast cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mast%20cell. Accessed 19 Feb. 2026.

Medical Definition

mast cell

noun
: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions

More from Merriam-Webster on mast cell

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster