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mast cell

noun

: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (such as histamine and heparin) which mediate allergic reactions

Examples of mast cell in a Sentence

Recent Examples on the Web
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Next, Platts-Mills sent some of the blood to the Mayo Clinic lab, which tested it for an enzyme called tryptase that’s made by immune cells called mast cells. Brenda Goodman, CNN Money, 14 Nov. 2025 The medication works by destabilizing mast cells, or allergy cells, to decrease allergic inflammation, says Rauno Joks, MD, an allergist and immunologist at NYC Health + Hospitals/Kings County in Brooklyn, New York, who was not involved in the study. Tom Gavin, EverydayHealth.com, 11 Sep. 2025 In fact, mast cells are covered in receptors for estrogen and progesterone, Wada says. Elizabeth Yuko, Flow Space, 29 Aug. 2025 Compared to mast cells elsewhere in the body, mast cells in the gut were primed to make leukotrienes. Hannah Millington, MSNBC Newsweek, 28 Aug. 2025 See All Example Sentences for mast cell

Word History

Etymology

partial translation of German Mastzelle, from Mast food, mast (from Old High German) + Zelle cell

First Known Use

circa 1890, in the meaning defined above

Time Traveler
The first known use of mast cell was circa 1890

Browse Nearby Words

Cite this Entry

“Mast cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mast%20cell. Accessed 30 Nov. 2025.

Medical Definition

mast cell

noun
: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions

More from Merriam-Webster on mast cell

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